One thing I'll remember from my childhood (well, late childhood, I guess) was the series finale of FAMILY TIES, specifically the part where the mom is at a school play for their youngest child but then imagines Alex standing up on stage basically saying, "You have to let me go, you have to let me move to New York" or wherever Alex was going. My mom started bawling at this, to the point that she had to leave the room. I think that was the first time I'd ever seen someone have that emotional of a reaction to something.
I haven't seen the finale since it aired, but for some reason, the following still sticks in my mind to this day:
"We can walk on hot coals,
and have ninjas fight us,
but be sure not to get
Gingivitis."